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Top 10 Best CBD Oils for Crohn’s Disease

Best CBD Oils for Crohns DiseaseThis article will cover the top 10 CBD oils for potentially helping those with Crohn’s Disease.

Crohn’s Disease, a type of inflammatory bowel disease, is a lifelong condition in which sections of the digestive system become painfully inflamed. The cause of Crohn’s Disease is currently unknown, although it is thought to be a result of genetic makeup or an issue with the immune system. Although the disease is not life-threatening, many people with Crohn’s Disease find it difficult to live healthy lives as symptoms and flare-ups frequently interrupt daily activities. These symptoms can include bloody stool, diarrhea, cramps, weight loss, or fatigue. Flare-ups can come at any time for Crohn’s patients, and it is nearly impossible to control the symptoms when they become present.

There is currently no cure for Crohn’s Disease, but there are a few treatments that can help manage it. Although mainstream medical research on CBD for Crohn’s is limited, many people have stated it helps them manage their symptoms. CBD has been frequently studied as an anti-inflammatory agent in the body, which is one of the leading symptoms of Crohn’s Disease. In this article, we will be discussing the top 10 CBD oils for Crohn’s Disease, so keep reading if you want our favorite recommendations.

1. 4 Corners Cannabis

Avocado Oil Tincture

4 corners best CBD for Crohns

Brothers Brian and Justin Jasiewicz started 4 Corners Cannabis out of a garage, a tiny kitchen, and a neighbor’s field in 2013. Today, it’s a well-known brand in the CBD world. The company is a true seed to shelf operation, tending and harvesting their own hemp, and extracting their CBD by using pure organic cane sugar alcohol, which they claim keeps the plant’s genetics intact. 

Their Earthy Avocado Oral Tincture is made with full-spectrum CBD and virgin organic avocado oil. It’s ideal for those with allergies to citrus or coconut. Choose from potencies ranging from 250 to 2000 mg of CBD per bottle. It comes with a graduated dropper for easy measuring. 

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2. Hemplucid

Full-Spectrum CBD Tincture

Hemplucid best CBD for Crohns

Hemplucid is on a mission to produce pure products that help people “experience life again”. They put a high priority on transparency (hence the name) and quality, providing some of the best CBD products you can find online. They have been selectively breeding hemp for over a decade, a practice they believe has produced genetically superior plants. 

The brand’s  Full-Spectrum CBD Tincture can be purchased with a hemp seed oil or and MCT oil carrier. Customers can choose from potencies as low as 250 mg to as high as 2000 mg of CBD in each dropper bottle. There are no artificial colors or flavorings, and they have a decidedly “hempy” taste. However, if you are looking for a pure CBD oil containing the whole range of cannabinoids and terpenes found in the plant, Hemplucid is an ideal choice. 

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3. Infinite CBD

CBD Isolate Droppers

Infinite best CBD for Crohns

Based out of Colorado, Infinite CBD is a company that does not use typical full-spectrum CBD oils, instead using only CBD isolate. Although you won’t have the benefit of the entourage effect with these products, CBD isolate contains no THC, so its ideal for those concerned about the addition of this cannabinoid. 

The CBD isolate droppers from Infinite can be purchased in concentrations ranging from 250 to 5000 mg of CBD in each bottle. The company uses coconut oil as a carrier oil for easy digestion and high bioavailability. They recommend taking the oil sublingually and letting it absorb for up to a minute. It can also be used topically by massaging it into the skin. 

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4. Elixinol

Daily Balance Liposome

elixinol CBD for Crohns

Elixinol is a brand offering some of the best CBD tinctures on the market. They’ve been working with hemp for over 25 years, and claim to have the most knowledgeable team of growers, extractors, formulators, and processors in the industry. Their CBD is CO2 extracted and sourced from US-grown hemp. It contains no chemicals or synthetic ingredients.

The brand offers several CBD formations, including full-spectrum, broad-spectrum, and organic oils. Their Daily Balance Liposome tincture stands out, however, due to the advanced technology used to produce it. By encapsulating CBD and MCT coconut oil in a phospholipid solution, they’ve created a product that is both fat and water-soluble. This process makes the CBD highly bioavailable to the cells.  

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Broad-Spectrum CBD Oil Tincture

CBDMD best cbd for crohns

CBDMD is a leading brand in the hemp industry, with years of solid ratings and a great safety profile. They offer an array of CBD products including gummies, tinctures, pet products, capsules, topicals, and more. Their products are made with broad-spectrum CBD. This ensures that they retain all of the beneficial terpenes and cannabinoids present in whole-plant formulations, but without any THC.

The 1000 mg broad-spectrum tincture is an inexpensive CBD oil available in natural, berry, orange, or mint flavor. It has been third-party lab tested in an ISO certified facility, and the results of that analysis can be viewed right on the product page. The company cautions that it may take two to three weeks of regular use to see results as it takes time for CBD to build up in the body.  


6. Green Gorilla

Organic Full-Spectrum CBD Oil

Green Gorilla best CBD for Crohns

Green Gorilla has created a line of proprietary CBD products that are unique from anything else on the market. This line is their Hemp & Olive line, which combines whole plant CBD with organic olive oil. This combination increases bioavailability and CBD’s impact on the body, as extra virgin olive oil already has many synergistic positive effects.

This full-spectrum oil is sourced from organically-grown hemp and can be purchased in potencies of 1200,2400, or 3000 mg of CBD per bottle. Unlike most brands that offer CBD in a dropper bottle, Green Gorilla utilizes a spray, which may be easier for some users. They recommend starting with five pumps a day. The brand uses only the aerial parts of the hemp plant to ensure all possible terpenes and flavonoids remain intact in the final formulation.

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7. Fab

CBD Oil Drops

FabCBD Best CBD for Crohns

Fab CBD is quickly becoming an industry leader with its array of popular products. The company uses only organically grown Colorado hemp for their CBD, and it is both CO2- extracted and third-party lab tested for quality assurance. 

Their CBD oil drops come in citrus, mint, vanilla, natural, or berry in your choice of potencies ranging from 300 to 2400 milligrams. They are non-GMO and made to order so you know you are getting a fresh product—not something that has been on the shelf for a while. The oil will keep for up to 12 months stored in a cool, dark place.  

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8. Endoca

300 Mg CBD Oil

endoca best cbd for crohns

For those new to CBD, this 300 mg CBD oil from Endoca is an ideal option. For starters, it is an inexpensive way to get started. But accurately measuring dosage to see how CBD oil affects you is another important factor for many. Endoca makes that an easy task. Each drop of oil contains one milligram of CBD, so adjusting the optimum dose for your needs is simple.

This is a true full-spectrum product, with all of the additional cannabinoids and terpenes intact. It’s sourced from organically-grown hemp and is GMP-certified. Endoca controls the entire process from seed to shelf, testing each product through an independent laboratory. The brand has been recognized by the UN for its sustainable practices. 

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9. NuLeaf Naturals

Full-Spectrum Hemp Oil

Nuleaf CBD for crohns

Founded in 2014 by plant medicine-focused entrepreneurs, NuLeaf Naturals is a company which is committed to crafting their products with care and ensuring the highest possible quality. They derive all of their hemp from Colorado and it has been grown using only sustainable and organic farming practices. Third-party lab results are readily available on the site. 

Their full-spectrum hemp oil tincture can be purchased in strengths ranging from 300 to 6000 mg, contains perfect no matter what potency you are looking for. The taste is rich and earthy. One drop is equivalent to 3mg of CBD, which makes it super-easy to calculate an accurate serving size. They recommend holding a dose of your discretion under the tongue for 30 seconds before swallowing to experience the full effects.

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10. Lazarus Naturals

High Potency CBD Isolate Tincture

lazarus best cbd for crohns

Lazarus Naturals was founded with the idea that everyone should have access to quality CBD products, regardless of their financial restrictions. Not only does the company make their products very affordable, but they also offer a 60% discount to veterans, those on disability, or those in low-income households.

Their high potency CBD isolate contains 3000mg of pure CBD in a two-ounce container, which is perfect if you’re looking for a CBD product that will last you a bit longer. Although you won’t get the added benefit of the entourage effect, you can be assured that this product is pure and contains no THC. The company recommends taking 1ml as needed and waiting up to two hours for the product to take full effect.

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Research on CBD and Crohn’s Disease

Among mainstream medical studies, CBD and Crohn’s Disease have had mixed results. In some situations, CBD has helped significantly in the treatment of Crohn’s Disease as well as with the patient’s general quality of life. However, other studies have presented findings that did not align with this idea. The consensus is that, although more research certainly needs to be done, CBD likely does help some people in the treatment of their Crohn’s Disease symptoms.

In a double-blind study conducted by Tel Aviv University in Israel, participants were given either a CBD treatment or a placebo, starting with 15mg a day and increasing according to the person’s reaction. On average, participants in the experimental group were taking 222 mg of CBD a day, as well as some THC.

The experimental group showed a significant improvement in both their symptoms and quality of life, but it was found that the inflammatory markers did not significantly improve. The takeaway from this kind of result is that while CBD could help people to achieve symptomatic relief, it should not currently replace a traditional form of treatment. However, this is not worthless information. Despite not being able to replace conventional therapeutic methods, CBD could certainly become a valuable addition.

In a 2018 study done by the University of Western Ontario in Canada, 93 participants were given whole-plant cannabis to test the effects of the compounds on Crohn’s Disease. The study was done over eight weeks, and the experimental group had some particularly interesting results. 45 percent of the group taking the cannabis went into full clinical remission when only 10 percent of the group taking the placebo did.

Additionally, 91 percent of the cannabis group had some significant medical response to cannabis, while only 40 percent of the placebo group had a response. While these findings are not exactly clear in their results, they do suggest that perhaps the relationship between cannabis and Crohn’s Disease could be significant.

In another 2018 study conducted by the University of Massachusetts and the University of Bath, England, it was suggested that cannabinoids could be used to prevent inflammation and maintain homeostasis. Since these are functions that the endocannabinoid system already carries out, this idea is not so far-fetched.

The study even suggested that cannabinoids could essentially “turn off” inflammation from irritable bowel disease. Throughout researching, scientists discovered that endocannabinoids travel along the lining of the gut and that these endocannabinoids are similar to the ones in cannabis.

Cannabinoids and Crohn’s Disease

It is hypothesized that when the human body does not have enough of these endocannabinoids, this is when gut inflammation can become irregular and result in painful symptoms. This hypothesis could explain why, when taking CBD, these cannabinoid levels improve symptoms.

CBD has a definite positive impact at least on Crohn’s Disease—at least anecdotally—as people continue to use it in their daily battle with their symptoms. This widespread use is likely because CBD works for many people with severe Crohn’s Disease, despite mainstream medicine not yet being able to prove it.

A great thing to consider when thinking about trying CBD for your Crohn’s Disease is that whether it works or not, you likely won’t suffer any ill effects. CBD has been proven to be non-addictive and has not shown to have any significant adverse side effects. It can also be stopped and started at any time without issues.

If you are suffering and can’t seem to find the answers, talk to your doctor about trying CBD for your symptoms.


These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

All content at Best Choice Reviews concerning CBD (Cannabidiol) or other health-related matters are for informational purposes only and are not to be considered as a substitute for medical advice, diagnosis, or treatment. If a reader has further questions about the use of these products, we encourage them to consult with a licensed physician or other qualified health care provider. The information included here is for educational purposes only and Best Choice Reviews is not responsible for inappropriate use of these products.